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Posts Tagged ‘Leukemia’

Leukemia is a disease of the blood and bone marrow that occurs on the background of genetic predispositions to cancer. Leukemia affects the cellular process of maturation, causing the accumulation of immature blood cells in the spinal marrow and bloodstream. In some cases leukemia causes the incomplete cells to multiply very quickly, while in other cases the abnormal blood cells have prolonged periods of life and persist in different places inside the body. Incomplete blood cells can’t substitute for normal blood cells, as they can’t carry out their roles. The cells affected by leukemia are therefore incompatible with the organism and can cause serious damage.

Judging by the speed of development and the persistence of the disorder, there are two types of leukemia: acute leukemia and chronic leukemia. Judging by the types of stem cells affected by the disorder, leukemia can either be lymphocytic or myelogenous.

Acute leukemia is different from chronic leukemia by the levels that stem cells are able to reach in their development (stem cells that present anomalies still manage to partially develop and either resemble immature cells or complete, normal white blood cells).

Acute leukemia is a form of cancer that develops very rapidly. It is manifested through overpopulation of the blood with immature cells that are unable to fulfill the functions of normal blood cells. In the case of acute leukemia, the marrow is unable to produce normal quantities of red blood cells, white blood cells and platelets. Patients who suffer from leukemia also develop anemia, a deficiency of normal red blood cells. Also, a decreased number of white blood cells reduces the body’s ability of overcoming infections, while the lack of platelets facilitates inflammation and bleeding.

Chronic leukemia tends to develop slower than acute leukemia. In the case of chronic leukemia, the body is able to produce blood cells that are more mature than those produced in acute leukemia. Although these cells may appear incomplete, they can’t fulfill their roles inside the organism and tend to cluster at different levels of the body. They also have a longer period of life.

Chronic leukemia of lymphocytic form is known to affect a type of blood cell called B lymphocyte. The disease weakens the immune system, interferes in the normal activity of the spinal marrow and facilitates the access of harmful cells to body organs. Chronic lymphocytic leukemia first occurs at the levels of the bone marrow, but can quickly spread to different organs and tissue through the bloodstream.

The presence of chronic lymphocytic leukemia is usually revealed by blood tests and careful body examination. Although apparently some people may have no symptoms of the disease, other patients may experience fatigue, lack of concentration, poor balance, memory loss, deterioration of vision and hearing, vertigos, body weakness, joint and bone pains. Just like in other forms of the disease, chronic leukemia requires immediate specific treatment and therapy. The chances of fully overcoming the disease are considerably enhanced if it is discovered quickly.

Finding a source of primitive stem cells.

There are news reports about the positive impact that research on cord blood stem cells is having on the possible cure for numerous life threatening diseases. But with so many varying reports about it or even factions it is impossible to keep track of all its useful facts. Stem cells show a great level of plasticity which means they can generate and regenerate into many different types of cells and even organs within in our body. Potentially, if they can be removed from the donor and transfused into the patient then in the future, stem cells could be used to cure virtually any illness.

Stem cells are more frequently found in babies or even in embryos although it has been discovered that adult stem cells do exist. To date these have mostly been found in the brain but are dispersed freely amongst millions of other cells making the extraction incredibly difficult.

Cord blood stem cells, on the other hand, are very easy to remove. Because the process is completed after the child has been born and the umbilical cord cut and clamped there is no effect whatsoever on the baby, the parent or the birth itself.

How stem cells become T cells.

T cells are the cells that are responsible for fighting infection in children and are created when stem cells pass through the thymus gland. If the patient does not have an adequate number of effective stem cells in their blood then they will not be able to create the T cells. And subsequently they are much more likely to suffer serious infections. This, in turn, means that cord blood stem cells can be used to recreate T cells as well as other vital cells within the body of your child. The stem cells will then create an army of T cells to fight off infection and leave the body to function in a normal manner. As with a blood transfusion it is imperative to the operation’s success that the stem cells transfused are of the same type as the patient’s own blood. Using cord blood stem cells belonging to the patient themselves all but guarantees that this will be the case.

Stem cell testing.

The umbilical cord stem cell matrix is called Wharton’s jelly and is rich in primitive stem cells. These cells are one that has yet to progress, transform or produce other cells. Primitive stem cells are the most effective type of stem cells that can be used in a transfusion on any patient.

Typically a lot of testing has been done on animals to prove the viability of using stem cells taken from cord blood of newborn babies and amongst the most prominent of these tests, according to the online journal “stem cells”, have been tests carried out on pigs. In a human blood cord, similar to a pig umbilical cord, two arteries & vein are found and tests have shown positive results concerned with the storage and potency of the blood. The journal “stem cells” contains a lot of data relating to stem cells and articles on various related topics.

At present leukemia and anemia are the two most common diseases treated with stem cell transfusions although since stem cell research has grown in volume and results diseases such as Parkinson’s, Multiple Sclerosis and many different forms of cancer are also showing positive results.